Mitoxantrone is an anthracycline antineoplastic agent
used in the treatment of certain types of cancer, mostly metastatic
breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma.
Mitoxantrone is also used to treat multiple sclerosis most notably the
subset known as secondary progressive MS. Mitoxantrone will not cure
multiple sclerosis, but is effective in slowing the progression of
secondary progressive MS and extending the time between relapses in
relapsing-remitting MS and progressive relapsing MS Mitoxantrone is a
type II topoisomerase inhibitor; it disrupts DNA synthesis and DNA
repair in both healthy cells and cancer cells.
CAS:70476-82-3
Molecular Formula:C22H28N4O6· 2HC1
Molecular Weight:517.41
Specifications:EP, USP
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