Magnetite and maghemite are preferred in biomedicine because they are biocompatible and potentially non-toxic to humans. Iron oxide nanoparticles is easily degradable and therefore useful for in vivo applications. Results from exposure of a human mesothelium cell line and a murine fibroblast cell line to seven industrially important nanoparticles showed a nanoparticle specific cytotoxic mechanism for uncoated Iron oxide nanoparticles.Solubility was found to strongly influence the cytotoxic response
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