The characteristics of carboxylated carbon nanotubes

Carbon nanotubes have been idealized as vehicles for drug and gene targeted cell. The physicochemical properties of carbon nanotube also promote its function as a "thermal antennas" for the destruction of non-invasive cancer. Covalent Modification of carbon nanotubes is a result of acid purification resulting in carboxylated carbon nanotubes. In addition, this covalent modification allows the attachment of biological fragments for cell targeting. in contrast, the carboxyl carbon nanotubes are proposed to be cytotoxic to mammalian cells. the current study examines the potential cytotoxicity of short, carboxylated nanotubes of multi-walled carbon in vitro model of fibroblast culture of primary cells. cytotoxicity was assessed by vital staining using propidium iodide, and the other with an assay of lactate dehydrogenase color. results indicate a cytotoxic dose dependent relationship between the nanotubes carboxylated multiwall carbon tested and semiconductor fibroblast culture cells model.Carboxylated and metallic carbon nanotubes under transverse electric fields are studied by the functional theory density based on first principles calculations. the external field polarizes the system, resulting in a dipole moment induced electric field to the incident with the module depends directly on the field strength. the structural and electronic properties of the resulting system due to orbital hybridization between the nanotube and COOH states are shown to be affected by the applied field. These results open new perspectives for alternative uses,
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