About Nandrolone decanoate

Nandrolone decanoate is used in the treatment of osteoporosis in postmenopausal women (though now not recommended) at a dose of 50 mg every three weeks. It is also used for some aplastic anemias. Nandrolone decanoate is perhaps the second-best known injectable anabolic steroid after testosterone. It seems that almost every steroid novice and many who are experienced with steroid cycles believe that for best results they may need to include Deca. However, in fact this compound has no special anabolic properties: other injectable steroids can do everything for muscle growth that Deca can.
An additional advantage of Deca Durabolin (nandrolone) is that this compound is relatively mild in terms of adverse side effects on the scalp and skin. This is because the 5-alpha reductase enzyme acts to reduce the potency of nandrolone, while in contrast many other anabolic steroids are unaffected by this enzyme, and testosterone’s potency is actually increased by it.

Catalog No: 3B3-004745
CAS No: 360-70-3
Molecular Formula: C28H44O3
Molecular Weight: 428.65

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About Testosterone Propionate

Of all the testosterone forms the effects of Testosterone Propionate are some of the most misunderstood. Many people tend to have a fair understanding of large ester compounds like Testosterone Enanthate, but when it comes to mixtures like Sustanon 250 or the small ester Testosterone Propionate the story changes. Over the years and this is largely thanks to steroid message boards the effects of Testosterone Propionate have been largely misconstrued. It’s very common for individuals to report and make claims that are impossible and make no sense if we actually understand the hormone, but that’s the problem. The problem is most don’t understand the hormone at all; in-fact, many assume things like Testosterone Enanthate and Testosterone Propionate are two very different steroids when they’re actually identical on a hormonal basis.
In any case, we want to take a good look at the effects of Testosterone Propionate. We want to you to understand how these effects manifest based on its small ester nature so that you can distinguish this form from other testosterone forms. Further, we want to look at the direct effects of Testosterone Propionate so that you know what to expect should you decide use is right for you.
This product is soluble in chloroform (50 mg/ml). It is also soluble in various oils. The oil solutions can be sterilized by maintaining at 150 deg C for 1 hour. It is practically insoluble in water, soluble 1 in 6 of ethanol, 1 in 4 of acetone, 1 in 20 of ethyl oleate, and 1 in 30 of propylene glycol. The product is incompatible with alkalis and oxidizing agents and it should be protected from light.
Testosterone Propionate  has been used for studying its effects on pregnant ewes
Catalog No: 3B3-004628
CAS No: 57-85-2
Molecular Formula: C22H32O3
Molecular Weight: 344.

what is Actidione ?

Cycloheximide,( Other names naramycin a, hizarocin actidione) is an inhibitor of protein biosynthesis in eukaryotic organisms, produced by the bacterium Streptomyces griseus. Cycloheximide exerts its effect by interfering with the translocation step in protein synthesis (movement of two tRNA molecules and mRNA in relation to the ribosome) thus blocking translational elongation. Cycloheximide is widely used in biomedical research to inhibit protein synthesis in eukaryotic cells studied in vitro (i.e. outside of organisms). It is inexpensive and works rapidly. Its effects are rapidly reversed by simply removing it from the culture medium.
Due to significant toxic side effects, including DNA damage, teratogenesis, and other reproductive effects (including birth defects and toxicity to sperm[1]), cycloheximide is generally used only in in vitro research applications, and is not suitable for human use as a therapeutic compound. Although it has been used as a fungicide in agricultural applications, this application is now decreasing as the health risks have become better understood.
Cycloheximide is degraded by alkali (pH > 7), decontamination of work surfaces and containers can be achieved by washing with a non-harmful alkali solution such as soap.
Actidione can be used as an experimental tool in molecular biology to determine the half-life of a protein. Treating cells with cycloheximide in a time-course experiment followed by Western blotting of the cell lysates for the protein of interest can show differences in protein half-life. Cycloheximide treatment provides the ability to observe the half-life of a protein without confounding contributions from transcription or translation.
It is used as a plant growth regulator to stimulate ethylene production. It is used as a rodenticide and other animal pesticide. It is also used in media to detect unwanted bacteria by suppressing yeasts and molds in beer fermentation.
The translational elongation freezing properties of Cycloheximide are also used for ribosome profiling / translational profiling. Translation is halted via the addition of Actidione , and the DNA/RNA in the cell is then nuclease treated. The ribosome-bound parts of RNA can then be sequenced.

what is perindopril erbumine ?

Perindopril is a long-acting ACE inhibitor. It is used to treat high blood pressure, heart failure or stable coronary artery disease in form of perindopril arginine  or perindopril erbumine . According to the Australian government's Pharmaceutical Benefits Scheme website, based on data provided to the Australian Department of Health and Aging by the manufacturer, perindopril arginine and perindopril erbumine are therapeutically equivalent and may be interchanged without differences in clinical effect. However the dose prescribed to achieve the same effect will differ due to different molecular weights for the two forms.
For Perindopril as treatment for hypertension, the initiation dose is 5 mg perindopril arginine (or 4 mg perindopril erbumine) once daily, then the dose may be increased to 10 mg perindopril arginine (or 8 mg perindopril erbumine) after 1 month of treatment to improve blood pressure control or in case of concomitant stable coronary artery disease.
The Anglo-Scandinavian Cardiac Outcomes Trial showed the benefits of taking the two drugs Perindopril and Amlodipine together. The 9000 British patients aged 40 to 79 were involved in the five-year trial. Half were given the new drug combination, the rest were given traditional drugs. Perindopril and Amlodipine were found to be so effective that the trial was stopped early so that all patients could receive the combination.
Each tablet contains 2 mg, 4 mg or 8 mg of the tert-butylamine salt of perindopril. Perindopril is also available under the trade name Coversyl Plus, containing 4 mg of perindopril combined with 1.25 mg indapamide.

about Nordihydroguaiaretic acid (NDGA)

Nordihydroguaiaretic acid (NDGA) is a potent antioxidant compound found in the creosote bush. It is believed that NDGA reduces cell damage by free radicals.
The plant has been used to treat a variety of illnesses including infertility, rheumatism, arthritis, diabetes, gallbladder and kidney stones, pain and inflammation, but its use is controversial. Nordihydroguaiaretic acid (NDGA) was widely used during the 1950s as a food preservative and to preserve natural fibers but was later banned after reports of toxicity during the early 1960s. Recently, it has been used as a nutritional supplement, however renal and hepatotoxicity are reported for chronic use of creosote bush and NDGA.
CAS:500-38-9
Molecular Formula:C18H22O4
Formula Weight:302.36
Description:
Melting point:180 - 185 C
Boiling point:526.5 °C at 760 mmHg
Flash Point:247.8 °C
Density:1.241 g/cm3
Chemical property:white to off-white powder.
Use:Antioxidant.
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what is Dimethyl sulfoxide (DMSO)

Dimethyl sulfoxide (DMSO) is a organosulfur compound.It is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water.In medicine, DMSO is predominantly used as a topical analgesic, a vehicle for topical application of pharmaceuticals, as an anti-inflammatory, and an antioxidant.
lthough it has some niche medicinal uses it also has significant known side effects. It has been discussed as treatment for cancer and other conditions.
Use of DMSO in medicine dates from around 1963, when an Oregon Health & Science University Medical School team, headed by Stanley Jacob, discovered it could penetrate the skin and other membranes without damaging them and could carry other compounds into a biological system. In medicine, DMSO is predominantly used as a topical analgesic, a vehicle for topical application of pharmaceuticals, as an anti-inflammatory, and an antioxidant. Because DMSO increases the rate of absorption of some compounds through organic tissues, including skin, it is used in some transdermal drug delivery systems. Its effect may be enhanced with the addition of EDTA. It is frequently compounded with antifungal medications, enabling them to penetrate not just skin but also toe and fingernails.

what is o-Phenylenediamine ?

o-Phenylenediamine is an organic compound with the formula C6H4(NH2)2. This aromatic diamine is an important precursor to many heterocyclic compounds. It is isomeric with m-phenylenediamine and p-phenylenediamine, and is commonly referred to as OPD.
o-Phenylenediamine condenses with ketones and aldehydes to give rise to a variety of useful products. Reactions with carboxylic acids and their derivatives afford benzimidazoles. The herbicide benomyl is prepared in this manner. Also, quinoxalinedione may be prepared by condensation of o-phenylenediamine with dimethyl oxalate. Condensation with xanthate esters affords mercaptoimidazoles, which are used as antioxidants in rubber products. Treatment with nitrous acid give benzotriazole, a corrosion inhibitor. Condensation of substituted o-phenylenediamine with various diketones is used in the preparation of a variety of pharmaceuticals.
In coordination chemistry, phenylenediamine is an important ligand precursor. Schiff base derivatives, such as those derived from salicylaldehyde, are excellent chelating ligands. Oxidation of its metal-phenylenediamine complexes affords the diimine derivatives, which are intensely colored and often exist in multiple stable oxidation states.
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use of Ceftriaxone

Ceftriaxone  is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram-positive and Gram-negative bacteria. In most cases, it is considered to be equivalent to cefotaxime in terms of safety and efficacy. Ceftriaxone sodium is marketed by Hoffman-La Roche under the trade name Rocephin, Rocetrax by Star Laboratories in Pakistan, as well as under various other names in several countries. Gepach International markets Ceftriaxone Injections under the brand name Cefatrin.

 Ceftriaxone is often used  for the treatment of community-acquired or mild to moderate health care-associated pneumonia. It is also a choice drug for treatment of bacterial meningitis. In pediatrics, it is commonly used in febrile infants between 4 and 8 weeks of age who are admitted to the hospital to exclude sepsis. The dosage for acute ear infection in the very young is 50 mg IM, one dose daily up to three days. It has also been used in the treatment of Lyme disease, typhoid fever, and gonorrhea.For the treatment of gonorrhea, a single intramuscular injection is usually given. According to the Journal of Family Practice, Volume 60, NO 12, December 2011, the intramuscular dose of ceftriaxone  has been increased from 125 mg IM to 250 mg IM due to increasing resistance of the gonococcal bacteria. It is also recommended that 100 mg of doxycycline be given orally at the same time for dual treatment. This takes care of treatment of underlying chlamydia, since treatment for chlamydia infection is also recommended. It must not be mixed or administered simultaneously  with calcium-containing solutions or products for patients younger than 28 days old, even via different infusion lines . 

CAS:73384-59-5
Molecular Formula:C18H18N8O7S3
Formula Weight:554.58
Specification:5g

Information about Boldenone undecylenate

Equipoise (boldenone undecylenate) is historically a veterinary steroid but for some time has been available as an UGL human preparation as well.
In the past, the principal reason for Equipoise’s use was it’s easy availability as a Mexican veterinary product. Presently, for the most part there is little specific reason to use Equipoise in an anabolic steroid cycle. There is nothing that it does anabolically that Masteron, Primobolan, Deca, or trenbolone will not do. In terms of side effects, likewise it has no advantage over Masteron or Primobolan, unless one desires the occasional side effect of increased appetite, or the side effect of its moderate conversion to estrogen. This can be useful if no other aromatizing steroid is being used.A serious drawback of Equipoise is its long half-life, which is probably at least 12 days. This results in an extended period of time after the last injection during which levels are neither sufficiently high for optimal anabolism, nor low enough to allow recovery to occur. A solution for this problem is to use Equipoise in only the earlier part of a cycle.Buy Equipoise (boldenone undecylenate)

About Hydroxyprogesterone Caproate

Hydroxyprogesterone Caproate(17α-Hydroxyprogesterone caproate )is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid).
17α-Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.
Cytyc is seeking FDA approval to market 17α-hydroxyprogesterone caproate under the trade name Gestiva for prevention of preterm delivery in women with a history of preterm delivery.
The use of 17-hydroxyprogesterone caproate in pregnancy to prevent preterm birth is not recommended without further study according to two authorities. A 2006 Cochrane Review concluded "...important maternal and infant outcomes have been poorly reported to date... information regarding the potential harms of progesterone therapy to prevent preterm birth is limited".There was a similar conclusion from a review by Marc Keirse of Flinders University. Three clinical studies in singleton pregnancies of 250 mg/week of intramuscular 17-hydroxyprogesterone caproate have all shown a trend for an increase in pregnancy loss due to miscarriage compared to placebo. The FDA expressed concern about miscarriage at the 2006 advisory committee meeting; the committee voted unanimously that further study was needed to evaluate the potential association of 17OHP-C with increased risk of second trimester miscarriage and stillbirth.

Use of Mupirocin

Mupirocin is used as a topical treatment for bacterial skin infections, for example, furuncle, impetigo, open wounds, etc. It is also useful in the treatment of methicillin-resistant Staphylococcus aureus (MRSA), which is a significant cause of death in hospitalized patients having received systemic antibiotic therapy. It is suggested, however, that mupirocin cannot be used for extended periods of time, or indiscriminately, as resistance does develop, and could, if it becomes widespread, destroy mupirocin's value as a treatment for MRSA. It may also result in overgrowth of non-susceptible organisms.

CAS : 12650-69-0
Molecular Formula : C₂₆H₄₄O₉
Formula Weight : 500.62

About Trandolapril

Trandolapril is almost white or pale yellow, slightly hygroscopic powder.The melting point is 122-123°C.It is freely soluble in glacial acetic acid. Its loss on drying is not more than 0.5% and the assay is not more than 98.0%.Its heavy metal is not more than 10ppm and residue on lgnition is not more than 0.15%.It is used for an  antihypertensive.It can also be used for an angiotensin converting enzyme (ACE) inhibitor. Trandolapril is a prodrug that is deesterified to trandolaprilat. It is believed to exert its antihypertensive effect through the renin-angiotensin-aldosterone system. Trandolapril has a half life of about 6 hours, and trandolaprilat has a half life of about 10. Trandolaprilat has about 8 times the activity of its parent drug. Approximately 1/3 of Trandolapril and its metabolites are excreted in the urine, and about 2/3 of trandolapril and its metabolites are excreted in the feces. Serum protein binding of trandolapril is about 80%.
CAS:87679-37-6
Molecular Formula:C24H34N2O5
Molecular Weight: 430.54g/mol

Ciprofloxacin hydrochloride

Ciprofloxacin is used to treat a number of infections, including infections of bones and joints, endocarditis, gastroenteritis, malignant otitis externa, respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, and chancroid. Ciprofloxacin is not recommended to treat community-acquired pneumonia (CAP) as a stand-alone first-line agent due to its modest activity against Streptococcus pneumoniae, a common causative pathogen. "Respiratory quiniolones" such as levofloxacin, having greater activity against this pathogen, are recommended as first line agents for the treatment of CAP in patients with important co-morbidities and in patients requiring hospitalization (Infectious Diseases Society of America 2007). The guidelines include a warning that "Data exist suggesting that resistance to macrolides and older fluoroquinolones (ciprofloxacin and levofloxacin) results in clinical failure.

Synonym: 3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE;3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE HYDRATE;CIPROFLOXACIN HCL;CIPROFLOXACIN HCL HYDRATE;CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATE;Ciprofloxacin Monohydrochloride;Ciflox;Ciproxan
Cas: 86483-48-9
MF: C17H19ClFN3O3
MW: 367.8
Melting point: >300°C.
Appearance: White or light yellow crystalline powder.
Used: Broad-spectrum antimicrobial medicines.
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What is Dexamethasone ?

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant effects. It is 25 times more potent than cortisol in its glucocorticoid effect, while having minimal mineralocorticoid effect.Dexamethasone is used to treat many inflammatory and autoimmune conditions, such as rheumatoid arthritis and bronchospasm.Idiopathic thrombocytopenic purpura, decreased numbers of platelets due to an immune problem, responds to 40 mg daily for four days; it may be administered in 14-day cycles. It is unclear whether dexamethasone in this condition is significantly better than other glucocorticoids.
It is also given in small amounts before and/or after some forms of dental surgery, such as the extraction of the wisdom teeth, an operation which often leaves the patient with puffy, swollen cheeks.
It is injected into the heel when treating plantar fasciitis, sometimes in conjunction with triamcinolone acetonide.
It is useful to counteract allergic anaphylactic shock, if given in high doses.Cancer patients undergoing chemotherapy are given dexamethasone to counteract certain side effects of their antitumor treatment. Dexamethasone can augment the antiemetic effect of 5-HT3 receptor antagonists, such as ondansetron.
In brain tumors (primary or metastatic), dexamethasone is used to counteract the development of edema, which could eventually compress other brain structures. It is also given in cord compression, where a tumor is compressing the spinal cord.

Desloratadine

Desloratadine is a drug used to treat allergies. It is marketed under several trade names such as NeoClarityn, Claramax, Clarinex, Aerius and Delot . It is an active metabolite of loratadine, which is also on the market.
Desloratadine is a tricyclic antihistamine, which has a selective and peripheral H1-antagonist action. It is an antagonist at histamine H1 receptors, and an antagonist at all subtypes of the muscarinic acetylcholine receptor. It has a long-lasting effect and in moderate and low doses, does not cause drowsiness because it does not readily enter the central nervous system. Unlike other antihistamines, desloratadine is also effective in relieving nasal congestion, particularly in patients with allergic rhinitis. Desloratadine is available as tablets (including orally disintegrating and extended release) and as syrup. In Colombia (South America) it is marketed under Dexio from Laboratorios Bussié, as tablets and as syrup to children. In Nepal and India it is widely available under the trade name Daziti and Dazit.

About Enalapril

Enalapril  is an angiotensin converting enzyme (ACE) inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. ACE converts the peptide hormone angiotensin I to angiotensin II. One of the actions of angiotensin II is the vasoconstriction of blood vessels resulting in an increase in blood pressure. ACE inhibitors such as enalapril prevent this effect. Enalapril has been shown to lower the death rate in systolic heart failure. Enalapril was the first member of the group known as the dicarboxylate-containing ACE inhibitors.

CAS : 75847-73-3
Molecular Formula : C₂₀H₂₈N₂O₅
Formula Weight : 376.45

About Desmopressin

Desmopressin (trade names: DDAVP, DesmoMelt, Stimate, Minirin) is a synthetic replacement for vasopressin, the hormone that reduces urine production. It may be taken nasally, intravenously, or as an oral or sublingual tablet. Physicians prescribe desmopressin most frequently for treatment of diabetes insipidus, bedwetting, or nocturia.Desmopressin is a modified form of the normal human hormone arginine vasopressin, a peptide containing nine amino acids.
Compared to vasopressin, desmopressin's first amino acid has been deaminated, and the arginine at the eighth position is in the dextro rather than the levo form .Doctors prescribe desmopressin frequently for treatment. It is usually in the form of desmopressin acetate, DDAVP. Patients taking DDAVP are 4.5 times more likely to sleep without disruption than with placebo. Examples of these situations are overnight camp and sleepovers.
US drug regulators banned treating bedwetting with desmopressin nasal sprays after two patients died and 59 other patients suffered seizures. The patients were using desmopressin when they developed hyponatremia, an imbalance of the body's sodium levels.
FDA regulators said that desmopressin tablets could still be considered safe for nocturnal enuresis treatment, as long as the patient was otherwise healthy. Patients must stop taking desmopressin if they become sick and have severe vomiting and diarrhea, fever, the flu, or severe cold. They should also be very cautious during hot weather or following strenuous exercise that may make them thirsty.
A healthy body needs to maintain a balance of water and salt . If sodium levels become too low (hyponatremia) – either as a result of increased water take-up or reduced salt levels – a person may have seizures and, in extreme cases, may die.
CAS NO:16789-98-3
Molecular formula:C₄₆H₆₄N₁₄O₁₂S₂
Molecular weight: 1069.24
Appearance:White powder
Purity(by HPLC):  ≥98.00%～99.90%
Amino Acid Composition: ±10% of theoretical
Water Content(Karl Fischer): ≤4.80%
Acetate Content(HPIC):≤6.80%

Something About Oxytocin

Oxytocin (Oxt) is a mammalian neurohypophysial hormone,  that acts primarily as a neuromodulator in the brain.
Oxytocin plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction, in particular during and after childbirth. It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, and, after stimulation of the nipples, lactation. Both childbirth and milk ejection result from positive feedback mechanisms.
Recent studies have begun to investigate oxytocin's role in various behaviors, including orgasm, social recognition, pair bonding, anxiety, and maternal behaviors. For this reason, it is sometimes referred to as the "bonding hormone". There is some evidence that oxytocin promotes ethnocentric behavior, incorporating the trust and empathy of in-groups with their suspicion and rejection of outsiders. Furthermore, genetic differences in the oxytocin receptor gene (OXTR) have been associated with maladaptive social traits such as aggressive behaviour.

The oxytocin peptide is synthesized as an inactive precursor protein from the OXT gene. This precursor protein also includes the oxytocin carrier protein neurophysin I. The inactive precursor protein is progressively hydrolyzed into smaller fragments  via a series of enzymes. The last hydrolysis that releases the active oxytocin nonapeptide is catalyzed by peptidylglycine alpha-amidating monooxygenase (PAM).
The activity of the PAM enzyme system is dependent upon vitamin C (ascorbate), which is a necessary vitamin cofactor. By chance, sodium ascorbate by itself was found to stimulate the production of oxytocin from ovarian tissue over a range of concentrations in a dose-dependent manner. Many of the same tissues  where PAM  is found are also known to store higher concentrations of vitamin C.

information about vitamin D

Cholecalciferol (also known as toxiferol) is a form of vitamin D, also called vitamin D3.
It is structurally similar to steroids such as testosterone, cholesterol, and cortisol (though vitamin D3 itself is a secosteroid).

Cholecalciferol is produced industrially for use in vitamin supplements and to fortify foods by the ultraviolet irradiation of 7-dehydrocholesterol extracted from lanolin found in sheep's wool. Paraphrasing a more detailed explanation,cholesterol is extracted from wool grease and wool wax alcohols obtained from the cleaning of wool after shearing. The cholesterol undergoes a four step process to make 7-dehydrocholesterol, the same compound that is stored in the skin of animals. The 7-dehydrocholesterol is then irradiated with ultra violet light. Some unwanted isomers are formed during irradiation. These are removed by various techniques, leaving a resin which melts at about room temperature and usually has a potency of 25,000,000 to 30,000,000 International Units per gram. Cholecalciferol is also produced industrially for use in vitamin supplements from lichens, which is suitable for vegetarians and vegans.
An alternative compound is ergocalciferol (also known as vitamin D2) derived from the fungal sterol ergosterol.

About Hyaluronic acid

Hyaluronan (also called hyaluronic acid or hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions.One of the chief components of the extracellular matrix, hyaluronan contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors.
CAS:     9004-61-9
Molecular Formula:C14H22NNaO11
Formula Weight:403.31
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Atorvastatin calcium

Atorvastatin calcium is a synthetic lipid-lowering agent.Atorvastatin is an inhibitor of 3 hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Atorvastatin calcium is a white to off-white crystalline powder that is insoluble in aqueous solutions of pH 4 and below. Atorvastatin calcium is very slightly soluble in distilled water, pH 7.4 phosphate buffer, and acetonitrile, slightly soluble in ethanol, and freely soluble in methanol.

Molecular Formula:C66H68CaF2N4O10
Molecular Weight:1155.36
CAS Number:134523-03-8
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Amlodipine besylate

 Amlodipine belongs to a class of medications called calcium channel blockers (CCBs). These medications block the transport of calcium into the smooth muscle cells lining the arteries of the heart (coronary arteries) and other arteries of the body. Since the action of calcium is important for muscle contraction, blocking calcium transport relaxes arterial muscles and expands (dilates) coronary arteries and other arteries of the body. By dilating coronary arteries, amlodipine increases the flow of blood to the heart and is useful in preventing heart pain (angina) resulting from reduced flow of blood to the heart caused by coronary artery spasm (contraction). Relaxing the muscles lining the arteries in the rest of the body lowers blood pressure, which reduces the work that the heart must do to pump blood to the body. Reducing the work of the heart also lessens the heart muscle's need for oxygen, and thereby further helps to prevent angina in patients with coronary artery disease. Combining amlodipine with sildenafil (Viagra) and similar drugs used for treating erectile dysfunction may lead to excessive reductions in blood pressure with complications, particularly fainting upon standing (orthostatic hypotension).
Amlodipine significantly increases blood levels of simvastatin (Zocor). The dose of simvastatin should be limited to 20 mg daily by patients taking amlodipine.

What is Isoprinosine

Isoprinosine, also known as Imunovir has been recommended as an adjuvant treatment for cancer, age-associated immune impairments and AIDS.Isoprinosine is an immunostimulator, which besides its immunomodulatory effect also has antiviral properties. It is used in the treatment of acute and chronic viral infections. Isoprinosine acts on the immune system to restore impaired cell-mediated immune response to its baseline level, in addition to enhancing humoral immune response. The drug also has a direct antiviral activity. Isoprinosine can reduce the intensity of symptoms and shorten the duration of the viral infection. In addition, the occurrence of complications is reduced and the frequency and severity of recurrences is minimised.
CAS No.:36703-88-5

Synonyms: Inosiplex;methisoprinol;ariral;bodaril;viac;delimmun;Isoprin;

Molecular Formula:  C24H34N6O9 

Molecular Weight:1115.24

Use of Oxandrolone

Oxandrolone is widely used due to its exceptionally small level of androgenicity accompanied by moderate anabolic effect. Although oxandrolone is a 17-alpha alkylated steroid, its liver toxicity is very small as well. Studies have showed that a daily dose of 20 mg oxandrolone used in the course of 12 weeks had only a negligible impact on the increase of liver enzymes. As a DHT derivative, oxandrolone does not aromatize (convert to estrogen, which causes gynecomastia or male breast tissue). It also does not significantly influence the body's normal testosterone production (HPTA axis) at low dosages (20 mg). When dosages are high, the human body reacts by reducing the production of LH (luteinizing hormone), thinking endogenous testosterone production is too high; this in turn eliminates further stimulation of Leydig cells in the testicles, causing testicular atrophy (shrinking). Oxandrolone used in a dose of 20 mg/day suppressed endogenous testosterone by 67% after 12 weeks of therapy.
In a randomized, double-blind study, patients with 40% total body surface area burns were selected to receive standard burn care plus oxandrolone, or without oxandrolone. Those treated with oxandrolone showed improved body composition, preserved muscle mass and reduced hospital stay time

About Pancreatin

Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease. This mixture is used to treat conditions in which pancreatic secretions are deficient, such as surgical pancreatectomy, pancreatitis and cystic fibrosis. It has been claimed to help with food allergies, celiac disease, autoimmune disease, cancer and weight loss. Pancreatin is sometimes called "pancreatic acid", although it is neither a single chemical substance nor an acid. Pancreatin is an effective enzyme supplement for replacing missing pancreatic enzymes, and aids in the digestion of foods in cases of pancreatic insufficiency.
Pancreatin is usually obtained from the pancreas of pigs or cows. It is used as medicine.Pancreatin contains the enzymes amylase, lipase, and protease, which help to digest food. These digestive enzymes are normally produced by the pancreas.

Thrombin protein

Thrombin protein (Purity) is determined by SDS-PAGE analysis.Thrombin is an active enzyme in the earliest steps of the blood clot formation, generated from its circulating inactive precursor prothrombin. Thrombin is a glycoprotein formed by two peptides chains of 36 and 259 amino acids linked by disulfure bonds. Three important sites have been identified on the surface of the enzyme: The catalytic site that confers to the molecule its serine protease activity, the exosite one responsible for the binding of the substrate (fibrinogen or thrombin receptor) and the exosite two responsible for the binding of antithrombin III and inactivation of thrombin. The molecular mass of thrombin is 37 kDa.
Storage:Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles

Application:FuncS, Use at an assay dependent dilution. Specific activity, ~3800 NIH units/mg Note,activity is measured in a thrombin specific clotting assay, and compared to standardized NIH thrombin.

About Nitrocefin

Nitrocefin is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by various microbes. Beta-lactamase mediated resistance to beta-lactam antibiotics such as penicillin is a widespread mechanism of resistance for a number of bacteria including members of the Enterobacteriaceae family; a major group of enteric Gram-negative bacteria. Other methods for beta-lactamase detection exist including PCR; however, nitrocefin allows for rapid beta-lactamase detection using few materials and inexpensive equipment.
CAS No.:41906-86-9
Synonyms: NITROCEFIN;3-(2,4-DINITROSTYRYL)-(6R, 7R)-7-(2-THIENYLACETAMIDO)-CEPH-3-EM-4 CARBOXYLIC ACID, E-ISOMER;(6R)-3-[(E)-2-(2,4-Dinitrophenyl)ethenyl]-8-oxo-7α-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular Formula:  C21H16N4O8S2 

Molecular Weight: 516.5

About 2,4-Dinitrophenol

2,4-Dinitrophenol (2,4-DNP, or simply DNP), C6H4N2O5, is an inhibitor of efficient energy (ATP) production in cells with mitochondria. It uncouples oxidative phosphorylation by carrying protons across the mitochondrial membrane, leading to a rapid consumption of energy without generation of ATP. Prior to 1938 it was used as a dieting aid, but it is considered too toxic for that use today.
Dinitrophenols as a class of compounds, of which there are six members, do not occur naturally but are all manufactured compounds.
Commercial DNP is primarily used for scientific research and in manufacturing. It has been used at times to make dyes, other organic chemicals, and wood preservatives. DNP is a chemical intermediate in the production of some herbicides including dinoseb and dinoterb. It has also been used to make photographic developer and explosives.
2,4-Dinitrophenol is a yellow, crystalline solid that has a sweet, musty odor. It sublimes when carefully heated and is volatile with steam. It is soluble in ethyl acetate, acetone, chloroform, pyridine, carbon tetrachloride, toluene, alcohol, benzene, and aqueous alkaline solutions. Its crystalline sodium salts are also soluble in water. It forms explosive salts with alkalies and ammonia, and emits toxic fumes of nitrogen oxides when heated to decomposition.

About Minoxidil

Minoxidil  is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. It is available over the counter for treatment of androgenic alopecia, among other baldness treatments, but measurable changes disappear within months after discontinuation of treatment.

Minoxidil is generally well tolerated, but common side effects include burning or irritation of the eye, itching, redness or irritation at the treated area, as well as unwanted hair growth elsewhere on the body. Users should discontinue treatment and seek medical attention right away if they experience any of the following serious side effects: severe allergic reactions  chest pain, dizziness, fainting, tachycardia (rapid heartbeat), sudden and unexplained weight gain, or swelling of the hands and feet.
Paradoxically, hair loss is a common side effect of minoxidil treatment. Manufacturers note that minoxidil-induced hair loss is a common side effect and describe the process as "shedding". Although this phenomenon demonstrates that minoxidil is indeed affecting hair follicles, manufacturers offer no guarantee that the new hair loss will be replaced with hair growth. The speculated reason for this shedding is the encouragement of hairs already in the telogen phase to shed early.

About Baclofen

Baclofen  is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.Baclofen is widely used for the treatment of spastic movement disorders, especially in instances of spinal cord injury, spastic diplegia, Ataxia multiple sclerosis, amyotrophic lateral sclerosis , Peripheral neuropathy and trigeminal and glossopharyngeal neuralgias.
A beneficial property of baclofen is that tolerance does not seem to occur to a significant degree — baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some patients receiving intrathecal baclofen treatment.
Baclofen is primarily used for the treatment of spastic movement disorders, especially in instances of spinal cord injury, cerebral palsy, and multiple sclerosis. Its use in people with stroke or Parkinson disease is not recommended.A baclofen derivative, arbaclofen placarbil, is undergoing clinical trials for the treatment of symptoms of autism and fragile-X syndrome. Unlike common symptomatic treatments for autism, arbaclofen may reduce core symptoms including social withdrawal.

Effects of Testosterone-Decanoate

The side-effects of Testosterone-Decanoate will be the same as all testosterone compounds; after all, testosterone is the same hormone regardless of the ester attached. As this is the case, the side-effects of Testosterone-Decanoate will largely surround its strong aromatizing nature; aromatization referring to the conversion of testosterone into estrogen. As estrogen levels increase, if they get too high this can lead to some of the most commonly associated anabolic steroidal side-effects on earth, but thankfully there is hope. Testosterone is one of the best steroids on earth for healthy adult men; not only because of the benefits, but equally important is its high level of toleration; that alone is a massive benefit.
In any case, the side-effects of Testosterone-Decanoate largely fall into what we can aptly call possible side-effects, and this means they are in no way guaranteed. Further, each and every one of the possible side-effects of Testosterone-Decanoate are 100% avoidable when supplementation is undertaken by a healthy adult male; this means you do not have high blood pressure or cholesterol or any prostate issues. So what are the side-effects of Testosterone-Decanoate? The one most men worry about a great deal is gynecomastia or male-breast enlargement, and this is due to the excess estrogen buildup caused by this steroids aromatizing nature. As estrogen levels increase, the hormone binds to the receptors and promotes breast tissue growth, and that can be devastating to any man. In-order to combat this effect, your ultimate protection will come in the form of an Aromatase Inhibitor (AI) such as Anastrozole (Arimidex) or Letrozole (Femara). AI’s actively inhibit the aromatase process from occurring, and they even lower the body’s total estrogen levels; nothing will protect you from gynecomastia like an AI.

About Testosterone undecanoate

Testosterone undecanoate or testosterone undecylate is an ester of testosterone. This hormone is used in androgen replacement therapy primarily for the treatment of male hypogonadism, and is currently under research for use as a male contraceptive.Testosterone undecanoate (Test-ost-er-rone an-de-ca-no-ate) is a medicine which is used in testosterone replacement therapy.
Testosterone undecanoate contains a hormone which is similar to the hormone testosterone that is produced by the body. Testosterone is a male sex hormone that is responsible for the development of male characteristics. These include growth of hair on the face and body, deepening of the voice, muscle development and the development of the male genitalia. Testosterone is also important for maintaining libido and fertility in men. In men who do not produce enough testosterone, Testosterone undecanoate is used to reduce the effects of a low level of testosterone.

Triclosan

Triclosan is an antibacterial and antifungal agent. It is a polychloro phenoxy phenol. Despite being used in many consumer products, beyond its use in toothpaste to prevent gingivitis, there is no evidence according to the American Food and Drug Administration (FDA) that triclosan provides an extra benefit to health in other consumer products.Triclosan safety is currently under review by the FDA.
Triclosan has been used since 1972, and it is present in soaps (0.10-1.00%), shampoos, deodorants, toothpastes, mouth washes, and cleaning supplies, and is incorporated into an increasing number of consumer products, such as kitchen utensils, toys, bedding, socks, and trash bags.It is also found in health care settings in surgical scrubs and personnel hand washes.
The use of Triclosan  s an additive for plastic production for use in food packages has not been approved by the European Commission (EC). Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. In the United States, manufacturers of products containing triclosan must indicate it on the label. The ingredient is regulated as a cosmetic preservative within Europe and in accordance with the European Cosmetic Regulation all cosmetic ingredients have to be listed on the label

Nano-alumina wear-resistance powder used for coati

Nano-alumina wear-resistance powder is specially used for a variety of paint, primer, coating ,it can enhance wear resistance, increase hardness, and have good dispersion and good transparency,
Nano-alumina wear-resistance powder can play a reinforcing role in enhancing the coating's hardness and wear resistance, hardness increased with the addition increased.

Item no	JR-NL16	JR-NL17
Appearance	White powder	White powder
Content of alumina﹪ ≥	99.5	99.5
Surface Properties	hydrophobic	hydrophilic
BET(m2/g)	8-15	8-15
Particle size,D50	2-3um	1-2um

1. Nano-alumina wear-resistance powder  does not affect the adhesion and transparency of coating when it is added in coating.
2.The product can reduce the volume of shrinkage during curing ,and can improve the adhesion between the coating and the substrate.
3. The thermal stability of coating will increase with increasing the dosage

About Atorvastatin calcium

Atorvastatin calcium is a synthetic lipid-lowering agent.Atorvastatin is an inhibitor of 3 hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Atorvastatin calcium is a white to off-white crystalline powder that is insoluble in aqueous solutions of pH 4 and below. Atorvastatin calcium is very slightly soluble in distilled water, pH 7.4 phosphate buffer, and acetonitrile, slightly soluble in ethanol, and freely soluble in methanol.
Molecular Formula:C66H68CaF2N4O10
Molecular Weight:1155.36
CAS Number:134523-03-8
Buy Atorvastatin calcium .

Amlodipine besylate

Amlodipine besylate is chemically described as 3-Ethyl-5-methyl (±)-2-[(2-aminoethoxy)methyl]- 4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, monobenzenesulphonate. Its empirical formula is C₂₀H₂₅CIN₂O₅•C₆H₆O₃S,.
Amlodipine is used in the management of hypertension[1] and coronary artery disease.
Amlodipine besylate is a white crystalline powder with a molecular weight of 567.1. It is slightly soluble in water and sparingly soluble in ethanol. NORVASC (amlodipine besylate) Tablets are formulated as white tablets equivalent to 2.5, 5, and 10 mg of amlodipine for oral administration. In addition to the active ingredient, amlodipine besylate, each tablet contains the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, sodium starch glycolate, and magnesium stearate.

About Oxandrolone

Oxandrolone, also known as oxandrin, is a drug first synthesized by Raphael Pappo while at Searle Laboratories, now Pfizer Inc., under the trademark Anavar, and introduced into the United States in 1964. It is a synthetic anabolic steroid derivative of dihydrotestosterone with an oxygen atom replacing the 2 carbon and methylation in the 17 position.

Oxandrolone is widely used due to its exceptionally small level of androgenicity[citation needed] accompanied by moderate anabolic effect. Although oxandrolone is a 17-alpha alkylated steroid, its liver toxicity is very small as well. Studies have showed that a daily dose of 20 mg Oxandrolone  used in the course of 12 weeks had only a negligible impact on the increase of liver enzymes. As a DHT derivative, oxandrolone does not aromatize (convert to estrogen, which causes gynecomastia or male breast tissue). It also does not significantly influence the body's normal testosterone production (HPTA axis) at low dosages (20 mg). When dosages are high, the human body reacts by reducing the production of LH (luteinizing hormone), thinking endogenous testosterone production is too high; this in turn eliminates further stimulation of Leydig cells in the testicles, causing testicular atrophy (shrinking). Oxandrolone  sed in a dose of 20 mg/day suppressed endogenous testosterone by 67% after 12 weeks of therapy.
In a randomized, double-blind study, patients with 40% total body surface area burns were selected to receive standard burn care plus oxandrolone, or without oxandrolone. Those treated with oxandrolone showed improved body composition, preserved muscle mass and reduced hospital stay time.

Mitoxantrone hydrochloride

Mitoxantrone is an anthracycline antineoplastic agent used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma. Mitoxantrone is also used to treat multiple sclerosis most notably the subset known as secondary progressive MS. Mitoxantrone will not cure multiple sclerosis, but is effective in slowing the progression of secondary progressive MS and extending the time between relapses in relapsing-remitting MS and progressive relapsing MS Mitoxantrone is a type II topoisomerase inhibitor; it disrupts DNA synthesis and DNA repair in both healthy cells and cancer cells.

CAS:70476-82-3
Molecular Formula:C22H28N4O6· 2HC1
Molecular Weight:517.41
Specifications:EP, USP

Features of PBT 4815

Features:1)excellent electrical property
2)excellent temperature resistance, high heat distortion temperature.
3)excellent mechanic and chemical property
4)excellent weatherability
5)excellent wear property
6)excellent moldability
7)high resistance to fuels, oil, fats and many solvents

Specification:PBT glass fiber 15% reinforced injection molding grade.

PBT 1403G6

Features and applications of PBT 1403G6:
1 excellent mechanical properties, high mechanical strength, fatigue resistance and dimensional stability, creep is also small, the performance is also very little change in the condition of high temperature. The consumption of energy of PBT is lowest
 2 production of engineering plastics, which for the current situation of worldwide energy shortage, has the very vital significance.
3 heat aging resistance, UL temperature index enhanced up to 120-140 degrees, in addition, the outdoor long-term aging is also very good.
 4 good solvent resistance, no stress cracking. 5 Easy flame, up to UL94 grade V-0, with good affinity with the flame retardant, so easy to develop reactive or adding flame retardant grade, flame retardant products widely used in electrical and electronic industry. Set the PBT molding process characteristics and the process parameters: the process characteristics of PBT: 1.PBT has obvious melting point, melting point of 225-235 degrees, is a crystalline material, the crystallinity of up to 40%; the viscosity of 2.PBT melt affected by temperature than the shear stress is so big, therefore, in injection, injection pressure of PBT melt flow properties obviously; 3.PBT good fluidity in the molten state, low viscosity, second only to nylon, prone to "cast" phenomenon in the molding; 4.PBT molding anisotropy, water under high temperature degradation. Application: electronic and electrical appliances: no fuse breaker, electromagnetic switch, flyback transformer, electrical appliances, handle, connector shell; the car: the door handle, bumper, distributor cap, fenders, wire protective shell, wheel cover; industrial parts: OA fan, keyboard, fishing reel, parts, lamp shade;
Buy PBT 1403G6

PBT 4130

PBT is the toughest one thermal plastic material, it is semi crystalline materials, chemical stability, mechanical strength, electrical insulating properties and excellent thermal stability. Good stability of these materials in a broad range of environmental conditions. PBT moisture absorption is very weak. Non enhanced tensile strength of PBT is 50MPa, PBT tension strength of glass additive type 170MPa. Glass additives will lead to excessive material embrittlement. PBT; crystallization is rapid, which will lead to bending deformation caused by uneven cooling. For glass additive type of material, flow direction shrinkage can be reduced, but with the flow perpendicular to the direction of the shrinkage rate basically no difference and common materials. General material shrinkage between 1.5%~2.8%. The material between the contraction of 0.3%~1.6% contains 30% glass additive. The melting point (225 ℃) and high temperature deformation temperature is lower than the PET material. VEKA softening temperature is about 170 ℃. Glass transition temperature (glass trasitio temperature) at 22 ℃ to 43 ℃. The crystallization rate of PBT is very high, so its viscosity is very low, cycle time plastic parts processing typically low.

Features of PBT 4130:1)excellent electrical property
2)excellent temperature resistance, high heat distortion temperature.
3)excellent mechanic and chemical property
4)excellent weatherability
5)excellent wear property
6)excellent moldability
7)high resistance to fuels, oil, fats and many solvents

Specification:PBT glass fiber 15% reinforced injection molding grade.

The advantages and use of PBT 4130

Advantages: 

1, stability and mechanical properties of tensile strength and tensile modulus and nylon are similar; 

2, the friction coefficient with self-lubricating;

3, low water absorption; 

4, excellent electrical properties;

5, good dimensional stability; 6, chemical resistance, oil resistance, excellent.

Usage:

 1, electronic and electrical appliances: no fuse breaker, electromagnetic switch, flyback transformer, electrical appliance handle, connector, shell etc.;

2, the car: door handle, bumper, distributor cap, fenders, wire protective shell, wheel cover etc.;

3, industrial parts: OA fan, keyboard, fishing reel, parts, such as lamp.